Substance use Essay Example | Topics and Well Written Essays - 250 words - 2

Substance use - Essay Example It appears that availability of opioids and subcultural factors are key in opioid use† (Encylopedia of Mental Disorders par. 19). In recent times, opioid abuse has increased through being given routine 30-day prescriptions for opioids as painkillers for illnesses requiring only a day or two for the pain to subside (Kluger par.2). 2. Give some examples of the use of hallucinogenic plants or drugs in connection with religious practices. The article on hallucinogens published in Medical Discoveries indicates that hallucinogenic plants or drugs have been used in connection with religious practices. (1) â€Å"Medicine men, shamans, and other spiritual leaders have used natural hallucinogens found in plants and mushrooms since ancient times, believing in their power to help contact the spiritual world or mystical beings for guidance in serving their people† (par. 4); (2) â€Å"In Mexico, mushrooms called Psylocybe mexicana, which contain the fungi psilocybin and psilocin, hav e been used in religious rituals since the time of the Aztec civilization† (par. 6); (3) â€Å"Peyote is the only psychedelic agent that has been authorized by the federal government for limited use during Native American religious ceremonies† (par. 7). 3.

How Exterior Environments Effect The Home Depot Corporation Term Paper

How Exterior Environments Effect The Home Depot Corporation - Term Paper Example vironments, since the challenges brought in by these environments are sometimes considered instrumental in making organisations devise mechanisms of overcoming the challenges. The facet of any business operations is to make profit. However, for any organisation to maintain competitive advantage, several factors dictate the success of developing and maintaining competitive advantage. According to Aquinas (2008), one of these factors is the external environments such as social, cultural, religious, legal and political environments. This paper will articulate on these factors and outline their influences on businesses and particularly on The Home Depot Corporation. Apart from internal operations of an organisation, each of the above mentioned external factors have been identified as potential influences of the business. Each of these factors affects businesses in different ways. Nevertheless, the line of business and market determines the level of control that these environments have on the business. For instance, a fast food business would be influenced differently by culture as opposed to how a clothing business would be influenced by the same. In some sit uations, the external environment has been argued to have configured the internal operations of an organisation, something that leads to slow development or boosts organisations returns (Markham, 2011). For instance, cultural factors may force an organisation to design or come up with new products that suits the culture of the target market. Political factors may force organisations to operate under the current political environment, something that may end up affecting the business operations that can lead to losses or slow development. Hatch & Cunliffe (2013) argued that organisations that want to maintain competitive advantage must show their willingness to participating in corporate social responsibility (Parboteeah, & Cullen, 2013). Social responsibility entails handing back to the society by supporting

Human Genetic Disorder

Human Genetic Disorder HUMAN GENETIC DISORDER Introduction Human Genetic Disorder is a kind of illness which is caused by chromosomes or genes abnormalities. Some disorders like cancer are in part of genetic disorders but they can also be caused by environmental factors. Many disorders are quite rare and they affect one person in a million. There are some types of recessive gene disorders which have an advantage in heterozygous states in some environments. Both genetic and environmental factors play a role in development of any kind of disorder. Human genetic disorder is caused by abnormalities of individuals of genetic materials. There are four types of genetic disorders; single-gene, chromosomal, multifactorial and mitochondrial. Single gene disorder is caused by a single mutated gene. This disorder can be passed on in successive generations in various ways. This disorder is caused mainly by mutation or changes of the DNA sequence in one gene. Multifactorial is caused by a combination of mutation of multiple genes and environmental factors . Chromosomal is caused by abnormalities caused by chromosomes. Mitochondrial is a genetic disorder caused by mutation in the mitochondria nonchromosomal DNA (Driel, et.al, 57). Single-gene is caused by mutation in the DNA. Gene codes for proteins which are the molecules which carry out most of the work does most of functions in life and even make up various cellular structures. After gene mutation for its proteins product not to carry out its usual functions, this leads to disorder. There are many single-gene disorders which occur in one out of 200 births. Examples include sickle cell anemia, cystic fibrosis, Marfan syndrome, heredity hemochromatosis and Huntingtons disease. Single-gene disorders are hereditary in identifiable structures. Combination of mutation of multiple genes and environmental factors leads to multifactorial (Bennet, 896). There are various types of genes which influence vulnerability to breast cancer which has been found on different chromosomes. Due to complicated nature of chromosomes, this makes it difficult to analyze chromosomal and single-gene disorders. Most of the common chronic disorders are multifactorial. Examples of this di sorder include Alzheimers, high blood pressure, heart disease, diabetes, arthritis, obesity and cancer. Inheritance of multifactorial is associated with genetic characteristics like height, fingerprint, skin color and eye color (Watson, 44). Chromosomal disorder is associated with chromosomes. Chromosomes are distinct structures which make up protein and DNA. Chromosomes which are mainly the carriers of heritable materials like chromosome structures abnormalities as missing leads to disease. The major abnormalities of chromosomal can be detected using microscopic examination. Trisomy 21 or Down syndrome is a common disorder which occurs when one has copies of chromosome 21. Mitochondrial disorder caused by mutation in nonchromosomal mitochondria DNA. Many genes are named after the disorder they are associated with. The normal functioning of gene is encoded with protein and this is not associated with cause of illness. Diseases linked with genetics occur when genes are not in a position to work properly. The hemochromatosis gene really codes for membrane protein after mutation of the gene in a manner which prevents if from encoding a functional and normal protein products (Milunsky, 67). Human genetic disorder is mainly caused by different kind of gene known as variation or modification of gene known as mutation. There are many diseases which are associated with the aspects of genes. Some like cancer are caused by gene mutation. Mutation can occur randomly or due to exposure to the environment like smoke from cigarette. Some of genetic disorders are inherited. Mutated genes are passed down from one generation to another through a family and each child can inherit those genes which causes the disorder. Other genetic disorders are because of problems with different number of packages of genes known as chromosomes like Down syndrome. Human genetic disorders are the main cause of death, disability and human tragedy. It is rare to find in a family which is entirely free from any kind of genetic disorder. Genetic defects are mainly known to cause pregnancy loss in developed countries and several spontaneous miscarriages involve fetus with abnormal chromosomes (McKusick, 15 ). Human genetic disorder is caused by nondisjunction which is the failure of chromosomes to replicate during the Anaphase II. Genes lacking chromosomes are not able to produce an embryo which is viable. Nondisjunction is most often linked with 21st chromosome giving rise to Down syndrome which increases chances of developing Alzheimers disease. Human genetic disorder is caused by abnormal genes groups which are passed down from one generation to another. Spontaneous mutation of genes is caused by error in the replication of DNA resulting in substitution base or insertion or deletion of one or two pair base from the DNA. Other disorder like somatic genetic disease is caused by sudden appearance of abnormal type of gene in one part of the body like cancer. Others like chromosomal abnormality are caused by abnormalities in the structure of chromosomes causing Down syndrome (Green and Waterston, 1968). Human genetic disorder can be diagnosed. Genetic test can be performed to determine whether the person has or doesnt have the disease even as early as during fetus. This testing is known as antenatal testing. Chromosome test can also be performed to diagnose human genetic disorder. Diagnostic of human genetic disorder is conducted for chromosome disorders, congenital malformations, mental retardation, infertility, learning disabilities, miscarriages, metabolic and molecular disorders and paternity. There are available genetic services for all prenatal, pediatric and adult genetic disorders such as Alzheimers, cancer, heart disease and other late disease onsets. Defects of birth lead to death of infants. There are infants who are diagnosed with the main genetic disorders. Genes and DNA performs are arranged on chromosomes. There are no genes which really cause disease. Mutations in the genes caused serious genetic disorder. Gene mutation in chromosomes caused disorder. Not all mutatio ns of genes lead to genetic disorder because some are unexpressed without any noticeable effect to the organism (Baird, et.al, 678). Conclusion Human genetic disorder occurs due to abnormalities of individuals of genetic materials. Human genetic disorders are of different types depending on the causes. There are four types of genetic disorders; single-gene, chromosomal, multifactorial and mitochondrial. Genetic disorders are mainly caused by mutation of genes and DNA. Each type of disorder has different cause. For example chromosomal disorder is caused by mutation of chromosomes. Swap of DNA by chromosomes to form variety of the gene pool can result to disorder leading to exchange of regions. Through abnormalities of genes and chromosomes human genetic disorder occurs. Some disease like cancer is as a result of genetic disorder but they can occur because of environmental factors. Most human genetic disorders are rare and they affect one person in a million. Some recessive gene disorders give advantage to the heterozygous states in some environments. Works Cited Baird Anderson, et.al, â€Å"Genetic Disorders in Children and Young Adults: a Population Study,† American Journal of Human Genetics, Vol. 42, pp. 677-693, 2000 Insert Surname here 6 Bennet Robin, â€Å"Genetic Disorder and the Fetus: Diagnosis, Prevention and Treatment,† The American Journal of Human Genetics, Vol. 77, No. 5, 2005, pp. 896-897 Driel Marc, et.al, â€Å"A New Web-based Data Mining Tool for Identification of Candidate Genes for Human Genetic Disorder,† European Journal of Human Genetic, Vol. 11, 2003, pp.57-63 Green Ernest and Waterston Roy, â€Å"The Human Genome Project: Prospects and Implications for Clinical Medicine,† Journal of American Medical Association, Vol. 266, 1999, pp. 1966- 1975 McKusick Charles, History of Medical Genetics, in Emery and Rimoins Principles and Practice of Medical Genetics, Churchill Livingstone, Inc.: New York, 1996, p. 1-30 Milunsky Aubrey, Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, (5th Ed), JHU Press, 2005 Watson Jean, â€Å"The Human Genome Project: Past, Present, and Future,† Science, Vol. 248, 1990, pp. 44-49

Conflicts in the Epic of Beowulf Essay -- Epic of Beowulf Essay

Beowulf – the Conflicts  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚        Ã‚  Ã‚   J.D.A. Ogilvy and Donald C. Baker in â€Å"Beowulf’s Heroic Death† comment on the hero’s culpability in his final conflict:    . . .the author describes Beowulf and the dragon lying dead side by side and observes rather sententiously that it was a bad business fighting with a dragon or disturbing his hoard. Beowulf, he adds, had paid for the treasure with his life. Some commentators seem to consider this passage, combined with Wiglaf’s remarks about Beowulf’s insistence on fighting the dragon alone, as a criticism of Beowulf’s conduct (69).    Beowulf contains considerable conflict, both external and internal. Conflict is how one describes the relationship between the protagonist and antagonist in a literary work (Abrams 225). There is also another type of conflict which takes place within the mind of a given character. These two types of conflict occur within this poem.    H. L. Rogers in â€Å"Beowulf’s Three Great Fights† expresses his opinion as a literary critic regarding conflicts in the poem:    The superhuman forces are Fate, the heathen gods, or the Christian God; conflicts between them and the hero’s character are frequently found. . . .The treatment in the three great fights of the motives of weapons, treasure and society implies a moral idea in which the poet believed: that a man should not trust in the things of this world, for they will fail him. Another aspect of this idea comes out clearly in the account of the first fight: that a man should trust rather in God and in the natural powers God gives him, for these will not fail him(234-37).    King Hrothgar’s construction of Heorot and the subsequent enhancement of the joy of the Danes precipitated t... ...with repeated conflict!       WORKS CITED    Abrams, M. H. A Glossary of Literary Terms, 7th ed. New York: Harcourt Brace College Publishers, 1999. BEOWULF. From The Harvard Classics, Volume 49.   P.F. Collier & Son, 1910. Translated by Francis B. Gummere. http://wiretap.area.com/ftp.items/Library/Classic/beowulf.txt Clover, Carol F. â€Å"The Unferth Episode.† In The Beowulf Reader, edited by Peter S. Baker. New York: Garland Publishing, 2000. Ogilvy, J.D.A. and Donald C. Baker. â€Å"Beowulf’s Heroic Death.† In Readings on Beowulf, edited by Stephen P. Thompson. San Diego: Greenhaven Press,1998. Clark, George. Beowulf. Boston: Twayne Publishers, 1990. Rogers, H. L. â€Å"Beowulf’s Three Great Fights.† In An Anthology of Beowulf Criticism, edited by Lewis E. Nicholson. Notre Dame, IN: University of Notre Dame Press, 1963.

Location Based Social Networking Essay

Imagine yourself in a locality surrounded by strangers- a new city, a new state yet, no more totally strange. Check-in Yo!, update your profile and you are all set for the location. The location based social networking app Yo!Buddy is making you familiar with the society and locale wherever you are. You can see the like-minded interests and hobbies pursuant, neighbors and have chance to communicate with them. If you think you are not familiar with the ones you desire to go ahead and say ‘hello’, do not feel the set back. Yo! will show you everyone using the app around you, upto 5km. The further you go with Yo!, it has the feature to update and check-in your location, nearby people, activities and events. What more would you ask your locality to show you than what you desire- the users and chance to communicate with them. Yo! finds it simple and unique to bring your online friends and neighbor closer to you in your real life. When you meet your locality people online more often chances to meet them in real life increase much more. Who knows you go to a big mall and are just checked-in to find out that another of your neighbor or friend is nearby or even an online Facebook friend has come to visit the city. You might even be idling at home on a weekend to find another of the Yo! user nearby you too is idling. This makes your networking stronger with him/her. Yo! is mastering itself to provide you the platform so that every time you check-in, the GPS based Yo! records it for you and fellow users. You can even check-in Yo! through your Facebook profile, connect with your friends nearby and be updated on how about of them. The social networking on web is changing and applications like Yo! are changing it for our betterment. You have the world shrunk in a piece of computer.You have Facebook, Twitter to make friends & followers worldwide and network. Though most of the friends or followers you get through these are virtually available and you might not have them when you need them. We are traveling to distant places for various reasons and at a strange place we feel left alone, most of the time. We like to see and enjoy our stay, befriend the people around and see nice places or just sit in a corner and still be updated as who are doing what nearby. Imagine yourself to see and doing whatever you like. Imagine to be updated and also open to be welcomed and involved in the surrounding. Location based social networking is bringing the world more alive to you- on your android application, in your palm. You just have to give it a try: invite and spread it to people around you, check-in, update and you are all set to say ‘Yo! Buddy, Wassup!’

“Life Doesn’t Frighten Me” by Maya Angelou

1. The speaker takes on the stance that she is fearless against common fears in life. 2. She deals with her fears in an imaginary sort of way.   She faces them with a â€Å"magic charm† that she â€Å"keep[s] up [her] sleeve†, not in a realistic way by marching up to them and facing them with courage, for example. 3.The author denies that she actually has any fears.   â€Å"[M]agic†, the way she deals with her fears, is not real; therefore I believe she is in denial of her fears. 4. I don’t think the author is afraid of what anything in the actual poem.   I think that she has probably already faced and conquered these particular fears or been subjected to them at some point already in her life.   This is why she does not fear them because they are not unknown. 5. The author should not be afraid of these fears because they are mostly childhood fears. 6. I think she strongly refused to be afraid of them because they are childish fears. 7. If the author was actually afraid of shadows, noises, ghosts, dogs, being alone, strangers, and boys, I’d take it that she was very childish in her manners and had not been exposed to much in her life.   While most children fear these things initially, they grow up and overcome those fears as they face life.   I think that if the writer were to be afraid of these, she may possibly be classified in a stereotypical manner of a young girl, but certainly not a woman, especially in the twenty first century where â€Å"woman† suggest strength and power almost equal to that of â€Å"man†.   However, â€Å"girl† still holds the stereotype of weaker, frailer, and in need of being protected (from things such as fears). 8. I do not find it interesting at all that none of these things frighten the speaker.   I think the speaker is trying to be convey strength, but it is such an immature strength, that it is a very weak argument. 9.   According to the fifth stanza, the speaker seems to be saying that boys are nasty brutes who pick on the girls who appear to be extremely girly.   The speaker probably fits in physically and stereotypically with the children, but mentally, emotionally, and intellectually she is older since she can detach herself from life.   She is more artistic and free in that sense than her peers. 10.   Other indicators that the speaker is fearless is how she makes the ghosts go away â€Å"I go boo Make them shoo† and her sense that anything is possible â€Å"I can walk the ocean floor And never have to breathe.† 11.   Strangers in the dark frighten me slightly as do panthers, but only if they are loose! 12.   I think, again, that the things that are mentioned are more childhood fears by both sexes.   I think females have deeper fears than this and it is a maturity issue.   I don’t think this is a poem about being a strong woman.   I think it is more a poem about being able to be oneself and not fearing what others think.